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openguts matlab ver 1.1  (MathWorks Inc)
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Model comparison for reduced general unified threshold models of survival of fathead minnow (GUTS‐RED‐stochastic death [SD]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐SD are dominant rate constant, threshold for effects, killing rate constant, and background mortality. For <t>openGUTS</t> versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. zw = threshold for effects; hb = background mortality; k D = dominant rate constant; bw = killing rate constant.
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Model comparison for reduced general unified threshold models of survival of fathead minnow (GUTS‐RED‐stochastic death [SD]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐SD are dominant rate constant, threshold for effects, killing rate constant, and background mortality. For openGUTS versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. zw = threshold for effects; hb = background mortality; k D = dominant rate constant; bw = killing rate constant.

Journal: Environmental Toxicology and Chemistry

Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles

doi: 10.1002/etc.5348

Figure Lengend Snippet: Model comparison for reduced general unified threshold models of survival of fathead minnow (GUTS‐RED‐stochastic death [SD]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐SD are dominant rate constant, threshold for effects, killing rate constant, and background mortality. For openGUTS versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. zw = threshold for effects; hb = background mortality; k D = dominant rate constant; bw = killing rate constant.

Article Snippet: We applied three different GUTS softwares, including two openGUTS implementations (MATLAB® Ver 1.1 and Windows® Ver 1.1) and the statistical software R (R Foundation for Statistical Computing, ) package “morse” (Ver 3.2.5; Baudrot et al., ).

Techniques: Comparison

Model comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐IT are dominant rate constant, median of the threshold distribution, threshold distribution shape parameter, and background mortality. For openGUTS versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. mw = median of the threshold distribution; hb = background mortality; k D = dominant rate constant; beta = threshold distribution shape parameter.

Journal: Environmental Toxicology and Chemistry

Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles

doi: 10.1002/etc.5348

Figure Lengend Snippet: Model comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) across five different fish species: ( A ) sheepshead minnow, ( B ) common carp, ( C ) bluegill, ( D ) rainbow trout, and ( E ) fathead minnow (calibration was performed with acute and early life stage test). Estimated parameters for GUTS‐RED‐IT are dominant rate constant, median of the threshold distribution, threshold distribution shape parameter, and background mortality. For openGUTS versions, the best fit (dot) and 95% confidence interval (horizontal line) are displayed; for morse, the median (dot) and 95% credible intervals (horizontal line) of the posterior distributions are displayed. mw = median of the threshold distribution; hb = background mortality; k D = dominant rate constant; beta = threshold distribution shape parameter.

Article Snippet: We applied three different GUTS softwares, including two openGUTS implementations (MATLAB® Ver 1.1 and Windows® Ver 1.1) and the statistical software R (R Foundation for Statistical Computing, ) package “morse” (Ver 3.2.5; Baudrot et al., ).

Techniques: Comparison

Median lethal profile comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) implementations (circle = morse, triangle = openGUTS MATLAB®, square = openGUTS standalone) across five different fish species: sheepshead minnow, common carp, bluegill, rainbow trout, and fathead minnow (calibration was performed with acute and early life stage test) for exposure Scenario C. For openGUTS versions, the best fit (dot) and 95% confidence interval (vertical line) are displayed; for morse, the median (dot) and 95% credible intervals (vertical line) of the posterior distributions are displayed. LP50 = median lethal profile.

Journal: Environmental Toxicology and Chemistry

Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles

doi: 10.1002/etc.5348

Figure Lengend Snippet: Median lethal profile comparison for reduced general unified threshold models of survival of common carp (GUTS‐RED‐individual tolerance [IT]) implementations (circle = morse, triangle = openGUTS MATLAB®, square = openGUTS standalone) across five different fish species: sheepshead minnow, common carp, bluegill, rainbow trout, and fathead minnow (calibration was performed with acute and early life stage test) for exposure Scenario C. For openGUTS versions, the best fit (dot) and 95% confidence interval (vertical line) are displayed; for morse, the median (dot) and 95% credible intervals (vertical line) of the posterior distributions are displayed. LP50 = median lethal profile.

Article Snippet: We applied three different GUTS softwares, including two openGUTS implementations (MATLAB® Ver 1.1 and Windows® Ver 1.1) and the statistical software R (R Foundation for Statistical Computing, ) package “morse” (Ver 3.2.5; Baudrot et al., ).

Techniques: Comparison

Species sensitivity distributions (SSDs; red line) are cumulative probability distributions that estimate the percentage of species that are affected by a given concentration of a chemical. The concentration that affects 5% of the species is referred to as the 5% hazard concentration (black dashed line). The SSD was built on the median lethal profile estimated with reduced general unified threshold models of survival (GUTS‐RED; openGUTS standalone implementation is shown). Calibration for Pimephales promelas was performed using the acute and early life stage test. ( A–C ) Results for fathead minnow GUTS‐RED‐stochastic death (SD); ( D–F ) results for common carp GUTS‐RED‐IT. Insets ( A–C ) describe exposure profiles (shown in Figure ). LP50 = median lethal profile.

Journal: Environmental Toxicology and Chemistry

Article Title: Fish Species Sensitivity Ranking Depends on Pesticide Exposure Profiles

doi: 10.1002/etc.5348

Figure Lengend Snippet: Species sensitivity distributions (SSDs; red line) are cumulative probability distributions that estimate the percentage of species that are affected by a given concentration of a chemical. The concentration that affects 5% of the species is referred to as the 5% hazard concentration (black dashed line). The SSD was built on the median lethal profile estimated with reduced general unified threshold models of survival (GUTS‐RED; openGUTS standalone implementation is shown). Calibration for Pimephales promelas was performed using the acute and early life stage test. ( A–C ) Results for fathead minnow GUTS‐RED‐stochastic death (SD); ( D–F ) results for common carp GUTS‐RED‐IT. Insets ( A–C ) describe exposure profiles (shown in Figure ). LP50 = median lethal profile.

Article Snippet: We applied three different GUTS softwares, including two openGUTS implementations (MATLAB® Ver 1.1 and Windows® Ver 1.1) and the statistical software R (R Foundation for Statistical Computing, ) package “morse” (Ver 3.2.5; Baudrot et al., ).

Techniques: Concentration Assay